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Discovery Alters Prevailing View Of Splicing Regulation And Has Implications For Splicing Mutations Associated With Disease
There are always exceptions to a rule, even one that has prevailed for more than three decades, as demonstrated by a Cold Spring Harbor Laboratory (CSHL) study on RNA splicing, a cellular editing process...
Sun, 20 May 2012 00:00:00 PDT - Source:MedNewsToday

Glioblastoma Classification Revision Should Improve Patient Care
Radiation oncology researchers have revised the system used by doctors since the 1990s to determine the prognosis of people with glioblastoma, which is the most devastating of malignant brain tumors. The outdated system was devised for glioblastoma and related brain tumors that were treated by radiation therapy only, and it relied on clinical signs and symptoms...
Fri, 18 May 2012 01:00:00 PDT - Source:MedNewsToday

Patients With Muscle-Invasive Bladder Cancer Benefit From Accelerated Chemotherapy Given Before Surgery
For some patients with muscle-invasive bladder cancer, treatment may begin before they undergo cystectomy, or surgical removal of the bladder. They may be advised by oncologists to receive chemotherapy before surgery...
Fri, 18 May 2012 01:00:00 PDT - Source:MedNewsToday

Positive Survival Trend Seen In Phase I Study Of Temsirolimus, Capecitabine
A phase I clinical trial examining the safety of combining temsirolimus and capecitabine in advanced malignancies suggests the two agents can be given safely to patients...
Fri, 18 May 2012 00:00:00 PDT - Source:MedNewsToday

Lapatinib Combined With Cetuximab Overcomes Resistance In EGFR-Driven Tumors
Targeted therapies have been studied for years, but recent laboratory research is providing robust clues about drugs that might work better in combination, particularly in treating cancers that have become resistant to therapy. That kind of information is behind a novel clinical trial at Georgetown Lombardi Comprehensive Cancer Center that combines cetuximab and lapatinib...
Fri, 18 May 2012 00:00:00 PDT - Source:MedNewsToday

Make Or Break For Cellular Tissues
Models developed to study liquids are used to investigate the mechanics of cellular tissues, which could further our understanding of embryonic development and cancer In a study about to be published in EPJ E¹, French physicists from the Curie Institute in Paris have demonstrated that the behaviour of a thin layer of cells in contact with an unfavourable substrate is akin...
Fri, 18 May 2012 00:00:00 PDT - Source:MedNewsToday

Google Algorithm Finds Cancer Biomarkers
Seven proteins that can help physicians evaluate how aggressive a patient's cancer is and whether or not they should receive chemotherapy have been identified by German researchers...
Thu, 17 May 2012 14:00:00 PDT - Source:MedNewsToday

Groundbreaking Advance In Medical Diagnostics
Researchers have created an ultrasensitive biosensor that could open up new opportunities for early detection of cancer and "personalized medicine" tailored to the specific biochemistry of individual patients. The device, which could be several hundred times more sensitive than other biosensors, combines the attributes of two distinctly different types of sensors, said Muhammad A...
Thu, 17 May 2012 01:00:00 PDT - Source:MedNewsToday

Some Dietary Supplements May Increase Cancer Risk
Beta-carotene, selenium and folic acid - taken up to three times their recommended daily allowance, these supplements are probably harmless. But taken at much higher levels as some supplement manufacturers suggest, these three supplements have now been proven to increase the risk of developing a host of cancers...
Thu, 17 May 2012 01:00:00 PDT - Source:MedNewsToday

Under-Use Of Safer Kidney Cancer Surgery For Poorer, Sicker Medicare, Medicaid Patients
An increasingly common and safer type of surgery for kidney cancer is not as likely to be used for older, sicker and poorer patients who are uninsured or rely on Medicare or Medicaid for their health care, according to a new study by researchers at Henry Ford Hospital...
Thu, 17 May 2012 01:00:00 PDT - Source:MedNewsToday

Gender Comparison In Kidney Cancer Surgery
Women do better than men after surgical removal of part or all of a cancerous kidney, with fewer post-operative complications, including dying in the hospital, although they are more likely to receive blood transfusions related to their surgery. But Henry Ford Hospital researchers who documented these gender differences can't say why they exist...
Thu, 17 May 2012 01:00:00 PDT - Source:MedNewsToday

The Favored Treatment For Kidney Cancer Is Robot-Assisted Surgery
Robot-assisted surgery has replaced another minimally invasive operation as the main procedure to treat kidney cancer while sparing part of the diseased organ, and with comparable results, according to a new research study by Henry Ford Hospital urologists...
Thu, 17 May 2012 01:00:00 PDT - Source:MedNewsToday

Study Of A Pediatric Cancer Finds All Cancer Cells Are Not Created Equal
A study from Massachusetts General Hospital (MGH) researchers suggests that specific populations of tumor cells have different roles in the process by which tumors make new copies of themselves and grow...
Thu, 17 May 2012 00:00:00 PDT - Source:MedNewsToday

Rising Infertility And Cancer Rates Possibly Linked To Pharmaceuticals And Household Chemicals
According to the European Environment Agency (EEA), household products, cosmetics, pharmaceuticals and food all contain endocrine disrupting chemicals (EDCs) which may be causing significant increases in diabetes, obesity, cancers and increasing infertility...
Wed, 16 May 2012 10:00:00 PDT - Source:MedNewsToday

Specific Clinical Guidance Urgently Needed On Bone Cancer Drugs
Although bisphosphonate drugs can reduce pain and bone fractures in individuals with multiple myeloma, no one drug is superior, according to a systematic review of the current evidence of these drugs. The review is published in The Cochrane Library. Multiple myeloma is a type of cancer that grows in and on bones. The disease can cause fractures in the spine and long bones...
Wed, 16 May 2012 10:00:00 PDT - Source:MedNewsToday

Advanced Soft Tissue Sarcoma, Pazopanib Improves Progression-Free Survival
According to results of the PALETTE trial, treatment with pazopanib increased progression-free survival (PFS) almost three fold among patients with metastatic soft-tissue sarcoma whose disease had progressed following chemotherapy. The results are published Online First in The Lancet...
Wed, 16 May 2012 10:00:00 PDT - Source:MedNewsToday

Cell Signaling Breakthrough May Help Melanoma Treatment
The body's function of generating new cells and replacing dead ones usually works fine, but it is by no means perfect. The key to generating new cells is communication or signaling between cells, and if this process does not function properly, it can lead to uncontrolled cell growth, which is the basis for many cancers...
Wed, 16 May 2012 10:00:00 PDT - Source:MedNewsToday

Discovery Of New Gene Mutations Leads To Breakthrough In Understanding The Cause Of Bile Duct Cancer
A team of international scientists has made a significant breakthrough in understanding the cause of bile duct cancer, a deadly type of liver cancer. By identifying several new genes frequently mutated in bile duct cancers, researchers are paving the way for better understanding of how bile duct cancers develop. Their discovery is published online in Nature Genetics...
Wed, 16 May 2012 00:00:00 PDT - Source:MedNewsToday

Eye Cancer Tumors Likely To Spread Can Be Identified By Genetic Test
Researchers at Washington University School of Medicine in St. Louis have developed a genetic test that can accurately predict whether the most common form of eye cancer will spread to other parts of the body, particularly the liver...
Wed, 16 May 2012 00:00:00 PDT - Source:MedNewsToday

Proper Radiotherapy Targeting While The Patient Is Breathing
Radiotherapists are constantly battling in order to administer the correct dose of radiotherapy, as respiratory movement during radiotherapy poses a certain risk that a tumor receives either a dose that is insufficient, or the surrounding healthy tissue is being subjected to a potentially toxic over-dose. Dr...
Tue, 15 May 2012 15:00:00 PDT - Source:MedNewsToday

Staggered Cancer Drug Delivery Better Than All In One Go
The fact that treating cancer patients with multiple drugs often results in better outcomes than a single drug treatment is long been known amongst the medical profession. However, a MIT study published in the May 11 issue of Cell has just demonstrated that the order and timing of administering drugs may also have a dramatic impact...
Tue, 15 May 2012 14:00:00 PDT - Source:MedNewsToday

HPV Positive Throat Cancer Responds Well To Just Radiotherapy
New research from Denmark, presented at the 31st Conference of the European Society for Radiotherapy and Oncology (ESTRO31), revealed that even though the human papilloma virus (HPV) can trigger throat cancer, non-smoking or light smoking HPV-positive patients respond well to radiotherapy treatment alone without requiring harmful chemotherapy in addition...
Tue, 15 May 2012 06:00:00 PDT - Source:MedNewsToday

Greater Diversity Than Expected Found In Children's Brain Tumors
Paediatric brain tumours preserve specific characteristics of the normal cells from which they originate - a previously unknown circumstance with ramifications for how tumour cells respond to treatment. This has been shown by Uppsala researcher Fredrik Swartling together with colleagues in the U.S., Canada and England in a study that was published in the distinguished journal Cancer Cell...
Tue, 15 May 2012 03:00:00 PDT - Source:MedNewsToday

Drug Restores Faulty Tumor Suppressor, Kills Cancer
A new study describes a compound that selectively kills cancer cells by restoring the structure and function of one of the most commonly mutated proteins in human cancer, the "tumor suppressor" p53...
Tue, 15 May 2012 03:00:00 PDT - Source:MedNewsToday

Cancer In The Elderly: Research Fails To Keep Up With Demographic Change
New research showing that almost half of 13,000 patients with head and neck cancers had other health-related problems at the same time was one of the presentations in a special session at the 31st conference of the European Society for Radiotherapy and Oncology (ESTRO 31) [1]. The session highlighted the effect of the demographic time bomb caused by an increasingly ageing population...
Tue, 15 May 2012 00:00:00 PDT - Source:MedNewsToday





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